Wound Healing

Closing the Gap in Wound Healing Trials

Foot ulcer - Wound Healing Trials

At Integrium, we understand the complexities and challenges of wound healing.

Our dedicated team of investigators, project managers, biostatisticians and medical writers is experienced in the design, conduct and analysis of clinical trials to evaluate interventions intended to speed and improve wound healing and reduce scarring.

We work with key opinion leaders in dermatology, general surgery, burn surgery, plastic surgery, vascular surgery and podiatry.

Our clinical team has researched many types of acute and chronic wounds of various tissue types including:

  • Diabetic Foot Ulcers
  • Compassionate Use (Neonatal Premature Infant)
  • Venous Stasis Ulcers
  • Auto-grafting and Donor Sites in Burn Patients
  • Decubitus Ulcers
  • Toxic Epidermal Necrolysis (TENS)
  • Lower Extremity Ulcers
  • Acute Wounds
  • Dehisced Wounds
  • Surgical Wounds
  • Deep Partial Thickness Burns
  • Epidermolysis Bullosa
  • Partial Thickness Burns
  • Hand Contractures

Dedicated Project Managers ensure:

  • Proper preparation and placement of product to optimize wound healing
  • Effective training in debridement and wound care
  • Precise and accurate wound healing imaging and measurement
  • Correct interpretation of complete epithelialization to ensure standardization of research sites

We have experience with a broad range of therapies and interventions including:

  • Tissue Engineered Products
  • Platelet Derived Growth Factors (PDGF)
  • Living Skin Equivalents
  • Topical Gels
  • Regenerative Medicine
  • Anti-microbial Dressings
  • Cryopreserved Products
  • Hyperbaric Oxygen Chambers
  • Cell Cultured Products
  • Off Loading Devices
  • Dermal Substitutes
  • Silhouette Mobile TM Device

We accurately assess and stage the wound healing process, wound closure and scarring.

We know how to use multiple wound assessment methods, including surrogate endpoints and biomarkers, to increase the reliability and validity of results:

  • Wound Healing Measurements
  • Wound Scarring Scales
  • Digital Photography
  • Vancouver Scar Scale
  • Wound Tracings and Analysis
  • Visual Analog Scale