Our Founding Partners

Integrium was founded by thought leaders in the fields of cardiovascular and metabolic disease research. They sought to develop study programs and protocols based on their expertise and industry recognition, and their strong backgrounds as clinical investigators provide invaluable insight into the practical aspects of clinical research. Today, they continue to serve as expert advisors for our clients’ projects, contributing their extensive knowledge of drug development and clinical practice.

Founding Partners

David H.G. Smith, MD

David H.G. Smith, MD

David H. G. Smith, MD is one of the founding partners of Integrium and serves as the Chief Medical Officer. In this role, he oversees the Medical Affairs group, which provides pharmacovigilance and medical monitoring services. He also works closely with clients on program planning, protocol development and other key clinical matters. Dr. Smith brings substantial experience in clinical research and management to the operational capabilities of Integrium. His leadership has provided the visionary growth and ethical service bias essential in the contract services arena.Read More

“Our existence and continued growth has always been in response to client needs,” according to Dr. Smith. “From the very beginning, our clients, both in the clinical development and marketing sectors of the industry, came to us first for advice, and then for focused and efficient effort for the execution of well designed study programs and strategies. I am proud of the way Integrium has refined the critical relationship of scientific quality, regulatory muster and marketing relevance — understanding that all are essential to product advancement.”

Dr. Smith completed his training in internal medicine and cardiovascular disease at the Veterans Affairs Medical Center, Long Beach, California and at the University of California, Irvine.

Dr. Smith has participated actively in research in the fields of hypertension, hyperlipidemia, diabetes, ischemic heart disorders and exercise stress testing. He has special interests in the study of the renin-angiotensin system, disorders of arterial compliance and endothelial dysfunction, 24-hour ambulatory blood pressure monitoring and the general pharmacotherapy of cardiovascular disorders. In addition to acting as Chief Medical Officer on a number of large international, multicenter clinical trials, he has authored numerous journal articles, abstracts, and book chapters and has formally presented at scientific meetings. Dr. Smith is a member of several specialty organizations and has been designated as a Specialist in Clinical Hypertension.

Along with his leadership role, Dr. Smith has served many clients in the area of scientific and regulatory consultation and has further assisted sponsors with representation and participation in meetings held with the US Food and Drug Administration, as well international regulatory authorities.

Joel M. Neutel, MD

Joel M. Neutel, MD

Dr. Neutel has had extensive experience serving the biopharmaceutical industry in the areas of clinical and academic research, as well as marketing strategic planning. Dr. Neutel maintains major responsibility as Director of Research at the Orange County Research Center in Orange County, California and at the Memorial Research Medical Clinic in Long Beach, California, where he has served as Study Principal Investigator on many multinational cardiovascular trials.Read More

After receiving his medical degree at the University of Witwatersrand in Johannesburg, South Africa, Dr. Neutel completed his internship and residency in internal medicine at the Veterans Administration Medical Center in Long Beach and The University of California, Irvine. Dr. Neutel has authored numerous abstracts, journal articles and book chapters. He has conducted extensive research in such disciplines as cardiovascular medicine, endocrinology, and central nervous system disorders, with special attention to the pharmacotherapy of the diseases in these areas.